It is a weak opiate. This is a painkiller that can be given for moderate pain, often in combination with paracetamol and/or an NSAID.

Mode of action

Tramadol provides pain relief by acting on the spinal cord and brain. It ensures that the transmission of pain signals that take place there is muted. Tramadol can be administered orally, rectally, or intravenously. When taken orally, tramadol works approximately after 1-2 hours, and the duration of action is around 4-8 hours. Tramadol is broken down by the liver and excreted by the kidneys.


Tramadol can be used in moderate acute and chronic pain in which paracetamol and/or NSAIDs have too little effect. It also has some analgesic effects on nerve pain.


When taking tramadol orally, 50-100 mg is prescribed 2-4 x per day with a maximum of 400 mg per day. The amount per dose and number of administrations per day depending on the severity of the pain. For children, a dose of 1-2 mg/kg up to 4 times a day applies with a maximum of 400 mg per day. Tramadol is not prescribed for children under 1 year of age. The dose should be adjusted in case of liver or kidney problems.

Side effects

The most common side effects of tramadol are nausea, vomiting, and constipation. It can also cause drowsiness, confusion, and headaches. Less common side effects include diarrhea, fainting, and fatigue. Palpitations, chest tightness, and itching or rash are also less common side effects. If you experience these symptoms, please contact your doctor.

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